Chris Stutz
Ph.D. 2015
Previous Education
B. S. in Chemical Engineering
Michigan Technological University
Hometown
Brookville, OH (close to Dayton)
Current Research
Eric Shusta Research Group
Univeristy of Wiscsonsin-Madison
The blood-brain barrier (BBB) is characterized by the presence of specialized vasculature that prevent a large majority of proteins and other molecules from entering the brain. This barrier has long been labeled a "bottleneck" for delivering drugs to the brain for treatments of central nervous system disorders (for example: Alzheimer's, Parkinson's and stroke). My research involves mining combinatorial libraries of antibody fragments (scFv) for individual scFv that can get past the BBB and enter the brain.
Publications
Stutz CC, Zhang X, Shusta EV. Combinatorial Approaches for the Identification of Brain Drug Delivery Targets. 2013. Jun 19. [Abstract]